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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Spine (Phila Pa 1976). 2013 Oct 1;38(21):10.1097/BRS.0b013e3182a3d370. doi: 10.1097/BRS.0b013e3182a3d370

Figure 2. Radiographic assessment of spine demonstrating scoliosis and kyphosis in SHP2-deficient mice.

Figure 2

Using mouse genetic-engineering techniques, we induced SHP2-deficiency during a juvenile stage of mouse development. Severe scoliosis and kyphosis were identified in the SHP2-deficient mice at 12 weeks as assessed by x-ray (i.e. AP and lateral views).