Table 2.
Absorbance values (570 nm) representing islet viability measured by MTT.
Encapsulated islets | Non-encapsulated islets | ||||
---|---|---|---|---|---|
Normoxia | Hypoxia | Reduction by hypoxia (%) | Normoxia | Hypoxia | Reduction by hypoxia (%) |
0.15 ± 0.02 | 0.10 ± 0.01* | 33.8 ± 3.50 | 0.15 ± 0.02 | 0.09 ± 0.02* | 42.9 ± 5.20 |
*P < 0.002 for the effect of hypoxia, P < 0.2 for the comparison of hypoxia-induced reduction of viability for encapsulated versus non-encapsulated islets. Data are mean ± SEM for 12 separate experiments (two-five parallels per condition), one-four experiments per donor (five donors).