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. 2013 Dec 11;13(4):527–539. doi: 10.1102/1470-7330.2013.0048

Table 1.

Summary of the cancer types, pathogenesis, and prognostic significance of calcification in malignant abdominopelvic tumors

Primary Pathogenesis of calcification Prognostic significance
Epithelial Adenocarcinoma Colon Unknown Longer survival
Ovarian Usually psammomatous Worse survival
Pancreatic Psammomatous Unknown
Neuroendocrine Small bowel Fibrosis Unknown
Medullary thyroid Amyloid deposition Unknown
Mesenchymal Bone Osteosarcoma Mineralization of osteoid matrix Increases with increased differentiated tumor burden
Chondrosarcoma Mineralization of chondroid matrix Increases with increased differentiated tumor burden
Soft tissue Liposarcoma Metaplasia Worse prognosis
Osteosarcomatous or chondrosarcomatous differentiation
GIST, primary Intratumoral necrosis Unknown
GIST, treated Unknown Disease response
Lymphoid NHL, primary Necrosis Aggressive subtypes
HD, primary Fibrosis/degeneration Nodular sclerosing subtype
NHL or HD, treated Necrosis Disease response
Multiple myeloma Amyloid deposition Unknown
Germ cell tumor Mature elements: teeth, bone, cartilage Unknown
Immature elements: necrosis

GIST, gastrointestinal stromal tumor; NHL, non-Hodgkin lymphoma; HD, Hodgkin disease.