Figure 3.

Pedigree drawing of the family-1 and 2 with autosomal recessive LQTS1, probands are shown with an arrow. ECGs from the probands in two families are shown in the middle, with a QTc of 557 and 529 ms, respectively. Intronic mutation, c.387 −5 T > A in the KCNQ1 gene was found in the patients (shown in the bottom). Mutation was shown with an arrow. Non-filled circles and squares are non-carriers for the mutation. Affected individuals are shown as filled circles (female) and squares (male). Half filled squares and circles are individuals with heterozygote mutation. Deceased individuals are indicated by slashes, probands are indicated by an arrow and consanguineous marriage is indicated by = Exon − intron boundary is shown by a dotted line with arrow pointing toward exon.