Fig. 2.

Clustering of species by unique growth-supporting conditions. Predicted metabolic phenotypes on the variable growth-supporting nutrient conditions composed of different carbon, nitrogen, phosphorous, and sulfur nutrient sources in aerobic and anaerobic conditions. Strains are clustered based on their ability to sustain growth in each different environment. Rows represent individual strains, and columns represent different nutrient conditions. In general, strains clustered into their respective pathotypes of commensal E. coli strains, intestinal pathogenic E. coli strains, extra-intestinal pathogenic E. coli strains, and Shigella strains. An asterix symbol indicates those strains that clustered outside of their respective pathotype. All growth conditions are listed in Dataset S1.