(A) Amygdala ROI was defined based on the contrast US > fixation on day 1 (FDR < 0.05; x = −17, y = −12, z = −4). (B) On day 2, the BOLD time course of this region showed greater percent signal change to both reminded and nonreminded CS+ relative to CS− during early extinction. (C) As extinction progressed, the amygdala mean differential β weights (CS+ minus CS−) decreased for the reminded and nonreminded CS+. *P < 0.05 (one-tailed t-test); error bars, SEM.