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. 2013 Nov 25;110(50):20308–20313. doi: 10.1073/pnas.1314190110

Fig. 2.

Fig. 2.

OXT effects on NAcc responses. Both in the DSC (A) and RPL (B) study, the intranasal administration of OXT increased NAcc response to the female partner's face compared with a matched, but unfamiliar woman (OXT(Partner > Unfamiliar) > PLC(Partner > Unfamiliar); DSC: left peak MNI coordinates −6, 5, −5; t(114) = 3.22, PFWE < 0.01; right peak MNI coordinates 6, 2, −2; t(114) = 3.70, PFWE < 0.01; RPL: left peak MNI coordinates −9, 5, 1; t(152) = 2.40, PFWE = 0.052; right peak MNI coordinates 12, 2, 1; t(152) = 2.48, PFWE = 0.04; display threshold P < 0.05 uncorrected). Percent signal change in the bilateral NAcc showed the greatest response to the mate after OXT administration. Error bars indicate SEM. DSC, discovery; L, left hemisphere; NAcc, nucleus accumbens; OXT, oxytocin; PLC, placebo; R, right hemisphere; RPC, replication.