Fig. 6.
MiR-155 controls B-cell proliferation through SHIP-1 after BCR and FcγRIIB coligation. (A) Naïve spleen B cells were labeled with CFSE and stimulated with either intact IgG or F(ab’)2 anti-IgM for 3 d. Cell division was determined using FlowJo Proliferation Platform software. Results are representative of four independent experiments with eight mice per genotype. (B) Same as in A. F, (Fab’)2 anti-IgM; I, intact IgG anti-IgM. *P = 0.0003; **P = 0.0022; ∞P = 0.6097 determined by Student t test. Results are from four independent experiments with eight mice per genotype.