Fig. 2.

Phylogenetic tree generated by using MrBayes 3.2.1 (33) from a ClustalX2 alignment of representative BTP proteins. Sequences were obtained from the National Center for Biotechnology Information database. The interior node values are the clade credibility values (posterior probabilities) generated by MrBayes. Genes found to mediate chlorhexidine resistance in this study by heterologous expression in E. coli (Table 1) or using gene deletion strains (Fig. S4) are underlined. Genes found to be transcriptionally responsive to chlorhexidine exposure in this study, or elsewhere (9, 10) are marked with an asterisk (*).