Table 3.
Network comparison between the 3 B-cell lymphoma GRNs and the (A) TRN and (B) PPN.
(A) Transcriptional regulatory network (TRN) | |||||
---|---|---|---|---|---|
Shared genes (%) | Edges GRN | Edges TRN | Shared edges% | p-value | |
C3Net | 7915 | 6361 | 22,668 | 8 (0.125) | 0.045 |
BC3Net | 7915 | 39, 507 | 22, 668 | 33 (0.084) | 0.176 |
Aracne | 7915 | 210, 036 | 22, 668 | 134 (0.064) | 0.923 |
(B) Protein protein network (PPN) | |||||
Shared genes (%) | Edges GRN | Edges PPN | Shared edges% | p-value | |
C3Net | 7944 | 6429 | 100,074 | 145 (2.226) | 0 |
BC3Net | 7944 | 40,049 | 100,074 | 563 (1.406) | 0 |
Aracne | 7944 | 213,841 | 100,074 | 2110 (0.987) | 0 |
Here, shared genes and shared edges correspond to the genes and edges that can be found in a GRN and the (A) TRN and (B) PPN.