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. Author manuscript; available in PMC: 2013 Dec 16.
Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2011 Jun 8;0(6):10.1002/ajmg.b.31205. doi: 10.1002/ajmg.b.31205

Figure 2.

Figure 2

A core region of SNPs 2–5 within the 15-SNP haplotype includes rs933271, rs5993883, rs739368, and rs740603. The two populations display opposite patterns of homozygosity and frequency of haplotypes. The haplotype in which alleles are derived for rs933271, rs5993883, and rs740603 (T–T–C–A) is the most common in EAs and also has higher homozygosity than the three ancestral allele haplotype (C–G–C–G). The three derived allele haplotype is less common than the three ancestral allele haplotype in AAs and also has lower homozygosity. Graphics produced using the web-based Extended Haplotype Homozygosity Calculator and Plotter (http://ihg.gsf.de/cgi-bin/mueller/webehh.pl).