Table 3.
Haplotype | African- American (global p-value=0.187) | European-American (global p-value=0.020) | ||
---|---|---|---|---|
freq. | additive | freq. | additive | |
rs737866-rs4680-rs174696 | ||||
A-A-T | 0.203 | 0.6280 0.5299 |
0.347 | 2.8450 0.0044 |
G-G-T | 0.062 | -3.1880 0.0014 |
0.260 | -1.0410 0.2979 |
A-G-C | 0.455 | 0.2870 0.7744 |
0.105 | -1.8210 0.0685 |
A-G-T | 0.147 | 0.7140 0.4754 |
0.138 | 0.5110 0.6095 |
G-G-C | 0.070 | -0.0470 0.9625 |
0.007 | * |
A-A-C | 0.053 | 0.3190 0.7496 |
0.107 | -0.6020 0.5472 |
G-A-T | 0.008 | * | 0.029 | * |
G-A-C | 0.002 | * | 0.007 | * |
Asterisks (*) represent data excluded from this analysis (for haplotype frequency less than 0.05). After Bonferroni correction for 8 haplotypes in the rs737866-rs4680-rs174696 haplotype analysis, significances at p< 0.00625 (0.05/8) level are marked with bold and underlined.