Table 4.
Haplotype | African-American (global p-value=0.017) | European-American (global p-value=0.0001) | ||
---|---|---|---|---|
freq. (with/without) | p-value | freq.(with/without) | p-value | |
rs737866-rs4680-rs174696 | ||||
1. A-G-T | 0.123/0.150 | 0.3056 | 0.188/0.196 | 0.6946 |
2. A-G-C | 0.462/0.410 | 0.0144 | 0.082/0.102 | 0.0010 |
3. A-A-T | 0.196/0.249 | 0.0015 | 0.293/0.343 | 0.0494 |
4. A-A-C | 0.077/0.062 | 0.3163 | 0.120/0.083 | 0.0003 |
5. G-G-T | 0.050/0.043 | 0.9959 | 0.227/0.243 | 0.7671 |
6. G-G-C | 0.083/0.069 | 0.3381 | 0.008/0.011 | 0.6397 |
7. G-A-T | 0.001/0.004 | 0.1717 | 0.030/0.004 | 0.0122 |
8. G-A-C | - | - | 0.004/0.004 | 0.9665 |
After Bonferroni correction for total 8 haplotypes in rs737866-rs4680-rs174696 haplotype analysis, significance at 0.00625 (0.05/8) level are marked in italic bold.