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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Alzheimers Dement. 2013 Jul 15;10(2):187–195. doi: 10.1016/j.jalz.2013.02.012

Fig. 4.

Fig. 4

Amyloid-β precursor protein (AβPP) expression across the life span and after developmental exposure to lead (Pb). (A) Changes in life span profiles of AβPP protein expression in the cerebral cortex of control (Control), early Pb exposure group (PbE), adult Pb exposure group (PbA), and early and adult Pb exposure group (PbEA) measured by Western blot analysis as described in Methods. (B) Quantification of AβPP Western blot bands normalized to β-actin levels. (C) Life span messenger RNA (mRNA) levels of AβPP relative to glyceraldehyde-3-phosphate dehydrogenase. Each data point in the curve is the mean ± standard error of the mean. *P <.05 compared with control.