Common causes of cancer deaths in the United States with focus on never smokers. Total lung cancer deaths, estimated at 161,840 in 2008, have been split into ever smokers and never smokers. Error bars reflect that the number of lung cancer deaths in never smokers, including cases attributable to secondhand smoke exposure and cases not attributable to tobacco, are estimated to total 16,000 to 24,000 per year. (Adapted from Rudin CM, Avila-Tang E, Samet JM. Lung cancer in never smokers: a call to action. Clin Cancer Res 2009;15(18):5622–5; with permission.)