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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Behav Pharmacol. 2013 Apr;24(2):10.1097/FBP.0b013e32835efc5f. doi: 10.1097/FBP.0b013e32835efc5f

Table 1.

Mean (± SD) ED50 for substitution of test drugs and suppression of response rate amongst sham and ovariectomized (OVX) female rats.

Group Substitution
Response rate
Sham OVX Sham OVX
Ethanol 640 ± 141 592 ± 199 - -
Allopregnanolone 6.8 ± 3.1 5.8 ± 3.9 13.9 ± 1.2 13.2 ± 3.3
Pregnanolone 6.3 ± 4.2 638 ± 5.6 8.5 ± 4.0 7.1 ± 3.7
Pentobarbital 5.0 ± 3.2 2.9 ± 1.7 10.2 ± 4.8 6.5 ± 3.7
Midazolam 1.0 ± 1.0 0.6 ± 0.5 3.5 ± 1.9 1.9 ± 1.4
Dizocilpine 0.03 ± 0.01 0.04 ± 0.02 0.08 ± 0.01 0.06 ± 0.03
TFMPP 0.59 ± 0.36 0.34 ± 0.39 0.8 ± 0.6 0.6 ± 0.2
RU 24969 0.79 ± 0.38 0.38 ± 0.33 1.3 ± 0.4 0.8 ± 0.3*

OVX, ovariectomized.

*

p < 0.05.