. 2013 Nov 19;8(11):e80573. doi: 10.1371/journal.pone.0080573

Table 4. Multivariate associations (odds ratios) between the number of lifetime traumatic events and the subsequent onset of any physical condition, without and with adjustment for mental disorders.

Any physical condition onset	Multivariate Number Model¹		Multivariate Number Model (Adjusted for PTSD)²		Multivariate Number Model (Adjusted for all mental disorders - type)³
	OR	(95% C.I)	OR	(95% C.I)		OR	(95% C.I)
I. Lifetime traumatic events: number
1 event	1.5^*	(1.4–1.6)	1.5^*	(1.4–1.6)		1.5^*	(1.4–1.5)
2 events	1.8^*	(1.7–1.9)	1.8^*	(1.7–1.9)		1.7^*	(1.6–1.8)
3 events	2.0^*	(1.9–2.1)	2.0^*	(1.8–2.1)		1.9^*	(1.7–2.0)
4 events	2.1^*	(2.0–2.3)	2.1^*	(1.9–2.3)		2.0^*	(1.8–2.1)
5+ events	2.6^*	(2.3–2.8)	2.5^*	(2.2–2.7)		2.1^*	(2.0–2.3)
Joint effect of number of events, χ ² ₅		771.3^*		709.3^*			575.9^*
II. Lifetime mental disorders
Major depressive episode/dysthymia	-	-	-	-		1.2^*	(1.1–1.2)
Bipolar disorder (broad)	-	-	-	-		1.1	(0.9–1.2)
Panic disorder	-	-	-	-		1.2^*	(1.1–1.3)
Generalized anxiety disorder	-	-	-	-		1.1^*	(1.0–1.2)
Social phobia	-	-	-	-		1.2^*	(1.1–1.3)
Specific phobia	-	-	-	-		1.3^*	(1.2–1.4)
Agoraphobia without panic	-	-	-	-		1.1	(0.9–1.2)
Post-traumatic stress disorder	-	-	1.3^*	(1.2–1.4)		1.1	(1.0–1.2)
Obsessive compulsive disorder	-	-	-	-		1.3	(1.0–1.6)
Intermittent explosive disorder	-	-	-	-		1.2^*	(1.1–1.4)
Binge eating disorder	-	-	-	-		1.2	(1.0–1.5)
Bulimia nervosa	-	-	-	-		1.3^*	(1.1–1.6)
Alcohol abuse	-	-	-	-		1.2^*	(1.1–1.3)
Alcohol dependence	-	-	-	-		1.0	(0.9–1.2)
Drug abuse	-	-	-	-		1.0	(0.9–1.1)
Drug dependence	-	-	-	-		1.1	(0.9–1.3)

Significant at p<0.05 level, 2-sided test.

The model was estimated with dummy predictors for number of trauma types without any information about type of trauma, controlling for person-years, age-cohorts, gender, country, education and physical condition type.

The model was estimated with dummy predictors for number of trauma types without any information about type of trauma and additionally adjusted for PTSD, including the controls specified above.

The model was estimated with dummy predictors for number of trauma types without any information about type of trauma and additionally adjusted for all mental disorders, including the controls specified above.