Table 4. Type 1 error in ERF data analysis.
Not corrected | Constant corrected | VIFGC corrected* | PGC corrected | ||||||||||
Model | Frequency | λmedian | λregress | E | λmedian | λregress | E | λmedian | λregress | E | λmedian | λregress | E |
Recessive | all | 1.201 | 1.200 | 0.074 | 1.000 | 1.000 | 0.050 | 1.001 | 1.000 | 0.050 | 1.000 | 1.000 | 0.050 |
[0.05,0.25) | 1.105 | 1.109 | 0.063 | 0.921 | 0.924 | 0.042 | 0.993 | 0.997 | 0.050 | 0.998 | 1.002 | 0.051 | |
[0.25,0.5) | 1.188 | 1.180 | 0.072 | 0.989 | 0.983 | 0.048 | 1.005 | 0.999 | 0.050 | 0.998 | 0.992 | 0.050 | |
[0.5,0.75) | 1.240 | 1.252 | 0.079 | 1.033 | 1.043 | 0.055 | 1.004 | 1.013 | 0.051 | 0.996 | 1.006 | 0.051 | |
[0.75,0.95] | 1.273 | 1.261 | 0.081 | 1.061 | 1.051 | 0.056 | 1.001 | 0.991 | 0.049 | 1.008 | 0.999 | 0.050 | |
Additive | all | 1.298 | 1.302 | 0.086 | 1.000 | 1.003 | 0.051 | 0.997 | 1.000 | 0.050 | 0.996 | 1.000 | 0.050 |
[0.05,0.25) | 1.299 | 1.290 | 0.085 | 1.001 | 0.994 | 0.050 | 0.998 | 0.991 | 0.049 | 1.008 | 1.000 | 0.050 | |
[0.25,0.5) | 1.298 | 1.313 | 0.088 | 1.001 | 1.012 | 0.052 | 0.997 | 1.008 | 0.052 | 0.986 | 0.997 | 0.050 | |
[0.5,0.75) | 1.301 | 1.320 | 0.088 | 1.003 | 1.017 | 0.053 | 1.000 | 1.014 | 0.052 | 0.989 | 1.003 | 0.051 | |
[0.75,0.95] | 1.292 | 1.286 | 0.084 | 0.995 | 0.991 | 0.049 | 0.992 | 0.988 | 0.049 | 1.003 | 0.999 | 0.050 | |
Dominant | all | 1.202 | 1.203 | 0.074 | 1.000 | 1.001 | 0.050 | 1.000 | 1.000 | 0.050 | 1.000 | 1.000 | 0.050 |
[0.05,0.25) | 1.277 | 1.265 | 0.081 | 1.063 | 1.053 | 0.056 | 1.001 | 0.991 | 0.049 | 1.008 | 0.999 | 0.050 | |
[0.25,0.5) | 1.243 | 1.252 | 0.079 | 1.035 | 1.042 | 0.054 | 1.003 | 1.011 | 0.051 | 0.997 | 1.005 | 0.051 | |
[0.5,0.75) | 1.190 | 1.183 | 0.072 | 0.990 | 0.985 | 0.049 | 1.005 | 1.000 | 0.050 | 0.999 | 0.994 | 0.050 | |
[0.75,0.95] | 1.104 | 1.112 | 0.064 | 0.919 | 0.925 | 0.042 | 0.991 | 0.998 | 0.050 | 0.995 | 1.002 | 0.051 | |
Over-dominant | all | 1.133 | 1.123 | 0.064 | 1.000 | 0.991 | 0.049 | 1.011 | 1.000 | 0.050 | 1.011 | 1.000 | 0.050 |
[0.05,0.25) | 1.203 | 1.193 | 0.072 | 1.061 | 1.053 | 0.056 | 1.017 | 1.010 | 0.051 | 1.011 | 1.003 | 0.050 | |
[0.25,0.5) | 1.076 | 1.060 | 0.057 | 0.950 | 0.935 | 0.043 | 1.011 | 0.995 | 0.049 | 1.013 | 0.998 | 0.049 | |
[0.5,0.75) | 1.064 | 1.053 | 0.056 | 0.939 | 0.929 | 0.042 | 1.000 | 0.989 | 0.049 | 1.004 | 0.993 | 0.049 | |
[0.75,0.95] | 1.204 | 1.190 | 0.072 | 1.062 | 1.050 | 0.056 | 1.017 | 1.007 | 0.051 | 1.014 | 1.004 | 0.051 | |
Genotypic (df = 2) | all | 1.157 | 1.162 | 0.077 | 1.000 | 1.004 | 0.052 | 0.964 | 0.966 | 0.046 | 0.996 | 1.000 | 0.051 |
[0.05,0.25) | 1.163 | 1.159 | 0.077 | 1.005 | 1.002 | 0.052 | 0.973 | 0.969 | 0.047 | 1.004 | 1.001 | 0.051 | |
[0.25,0.5) | 1.152 | 1.165 | 0.077 | 0.996 | 1.006 | 0.052 | 0.954 | 0.964 | 0.045 | 0.988 | 0.999 | 0.051 | |
[0.5,0.75) | 1.151 | 1.164 | 0.077 | 0.995 | 1.006 | 0.052 | 0.953 | 0.963 | 0.046 | 0.989 | 1.000 | 0.051 | |
[0.75,0.95] | 1.163 | 1.159 | 0.077 | 1.005 | 1.001 | 0.052 | 0.973 | 0.970 | 0.047 | 1.004 | 1.000 | 0.052 |