Table 1.

Characteristics of all LQTS mutation carriers from the discovery cohort

	Caucasian	Japanese	All
LQT1	84 (59.2%)	36 (43.9%)	120 (53.6%)
LQT2	56 (39.4%)	46 (56.1%)	102 (45.5%)
LQT1+LQT2	2 (1.4%)	-	2 (0.9%)
Female	74 (52.1%)	43 (52.4%)	117 (52.2%)
Symptomatic	39 (52.7%)	26 (60.5%)	65 (55.6%)
Male	68 (47.9%)	39 (47.6%)	107 (47.8%)
Symptomatic	32 (47.1%)	15 (38.5%)	47 (43.9%)
Asymptomatic/Symptomatic gender
Female/Female	18 (25.4%)	9 (22.0%)	27 (24.1%)
Male/Male	15 (21.1%)	7 (17.1%)	22 (19.6%)
Female/Male	17 (23.9%)	8 (19.5%)	25 (22.3%)
Male/Female	21 (29.6%)	17 (41.5%)	38 (33.9%)
Age at first ECG (years)
Asymptomatic	49 ± 12	48 ± 10	48 ± 11
Symptomatic	19 ± 12	18 ± 9	19 ± 11
Cardiac events
Syncope	58 (81.7%)	41 (100%)	99 (88.4%)
Cardiac arrest and/or sudden cardiac death	13 (18.3%)	-	13 (11.6%)
Age at the time of the first cardiac event (years)
All symptomatic patients	14 ± 8	13 ± 5	13 ± 7
Female	17 ± 9	13 ± 5	15 ± 7
Male	11 ± 7	11 ± 5	11 ± 6
LQT1	12 ± 8	11 ± 5	12 ± 7
LQT2	17 ± 8	14 ± 5	16 ± 7
QTc (ms)
Female	480 ± 39	502 ± 50	483 ± 44
Male	473 ± 47	496 ± 56	470 ± 49

Data presented as n (%) or mean ± SD