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Enzyme-catalyzed pathways of amine groups transfer from L-alanine (Ala) to α-ketoglutarate (α-KG) into L-glutamate (Glu) and pyruvate (Pyr) (part A), and carboxylation of pyruvate into oxaloacetate (OxAl) (part B).
Notes: Part A adapted with permission from Filipowicz A, Wołowiec S. Bioconjugates of PAMAM dendrimers with trans-retinal, pyridoxal, and pyridoxal phosphate. Int J Nanomedicine. 2012;7:4819–4828. © Dovepress 2012.31
Abbreviations: CL, carboxylase; TA, transaminase.
