Figure 1.
Comparison of blood glucose and body weights of control and alogliptin-treated mice engrafted with human islets.
Notes: Diabetic NSG mice were transplanted with human islets from three individual donors and treated daily by gavage with alogliptin (n=5, each donor) or vehicle control (n=5, each donor). (A) Blood glucose and (B) body weight of the mice were monitored over the treatment period on the days indicated; shown are mean ± standard error of the mean. *P<0.05.
Abbreviation: NSG, NOD-scid IL2rγnull.