Figure 3. Tryptanthrin inhibited the migration of human microvascular endothelial cells.
HMEC-1 cells (5×105cells/well) were wounded by scratching with a 0.1 mL pipette tip and were incubated with solvent control (0.1% DMSO) or various concentrations of tryptanthrin for 8 h. (A) Representative appearance of the HMEC-1 cells at 0 h and 8 h. (B) Migration ability was evaluated by measuring the gap widths narrowed down by HMEC-1cells’movement. Data are expressed as mean ± SD. *** p<0.001.