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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Ann Epidemiol. 2013 Oct 12;24(1):10.1016/j.annepidem.2013.10.003. doi: 10.1016/j.annepidem.2013.10.003

Table 3.

Association between glutathione S-transferase gene variants and colorectal cancer

Cases/controls Unadjusted Adjusted
OR (95% CI) OR (95% CI)
GSTM1
 Null 201/379 1.00 1.00
 Non-null 134/259 0.99 (0.76, 1.30) 1.04 (0.78, 1.38)
GSTT1
 Null 173/318 1.00 1.00
 Non-null 164/350 0.86 (0.66, 1.12) 0.84 (0.63, 1.11)
GSTM1/GSTT1
 Both null 106/169 1.00 1.00
 One null/One non-null 159/336 0.75 (0.55, 1.03) 0.76 (0.54, 1.06)
 Both non-null 67/128 0.80 (0.55, 1.18) 0.83 (0.55, 1.24)
p trend 0.1977 0.2793

Adjusted models included age, BMI, leisure time physical activity, total energy intake, red meat intake, total meat intake, education, income, occupation, smoking, alcohol consumption and family history of cancer.