Table 4.
anatomical hits | cage area time (s) | corners time (s) | open field | interaction ratio | |||||
---|---|---|---|---|---|---|---|---|---|
empty cage | novel mouse | empty cage | novel mouse | center time (s) | distance (m) | cage area | corners | ||
|
|||||||||
females | aCSF (n=10) | 106.01 ± 8.87 | 111.98 ± 8.74 | 4.44 ± 1.61 | 7.12 ± 3.06 | 24.78 ± 5.15 | 22.91 ± 2.73 | 109.09 ± 8.03 | 194.44 ± 61.26 |
5ng (n=8) | 87.69 ± 13.85 | 103.20 ± 18.20 | 7.84 ± 1.71 | 6.06 ± 2.57 | 39.76 ± 10.15 | 20.15 ± 2.44 | 153.53 ± 43.10 | 328.68 ± 252.95 | |
50ng (n=7) | 90.09 ± 7.37 | 120.23 ± 10.75 | 11.87 ± 3.59 | 6.10 ± 3.84 | 23.23 ± 4.78 | 20.10 ± 4.19 | 135.66 ± 9.92 | 66.33 ± 19.95 | |
500ng (n=9) | 79.96 ± 11.43 | 62.99 ± 11.01* | 8.30 ± 2.47 | 10.49 ± 3.12 | 32.59 ± 7.33 | 24.15 ± 4.02 | 84.04 ± 10.22* | 164.24 ± 54.17 | |
males | aCSF (n=7) | 76.39 ± 11.11 | 88.47 ± 20.18 | 11.07 ± 1.71 | 34.90 ± 22.14 | 31.83 ± 7.99 | 16.20 ± 1.59 | 105.75 ± 17.30 | 263.92 ± 175.41 |
5ng (n=8) | 67.84 ± 9.05 | 93.08 ± 17.21 | 15.36 ± 3.64 | 8.89 ± 3.01 | 22.38 ± 4.61 | 20.23 ± 3.01 | 149.52 ± 28.66 | 82.41 ± 27.66 | |
50ng (n=8) | 75.15 ± 11.32 | 80.34 ± 19.11 | 8.83 ± 2.82 | 5.56 ± 1.58 | 31.08 ± 3.89 | 15.37 ± 2.32 | 102.97 ± 17.81 | 169.21 ± 94.90 | |
500ng (n=6) | 66.60 ± 13.00 | 77.33 ± 16.51 | 19.08 ± 9.54 | 33.33 ± 28.41 | 33.52 ± 5.18 | 14.44 ± 2.32 | 124.36 ± 39.38 | 227.65 ± 116.02 | |
anatomical misses | |||||||||
females | aCSF (n=8) | 91.43 ± 8.77 | 115.63 ± 8.94 | 4.26 ± 1.53 | 1.71 ± 0.86 | 25.03 ± 1.96 | 19.01 ± 1.96 | 129.08 ± 6.94 | 105.71 ± 80.94 |
5ng (n=5) | 80.90 ± 14.96 | 120.94 ± 19.51 | 11.26 ± 4.99 | 3.22 ± 1.66 | 33.24 ± 5.26 | 19.94 ± 3.72 | 163.85 ± 35.47 | 105.55 ± 86.63 | |
50ng (n=5) | 58.46 ± 14.30 | 83.40 ± 15.75 | 9.46 ± 2.10 | 6.12 ± 1.63 | 28.68 ± 6.17 | 25.59 ± 6.39 | 157.64 ± 32.96 | 63.07 ± 17.03 | |
500ng (n=3) | 79.53 ± 6.30 | 89.37 ± 42.51 | 10.27 ± 3.50 | 5.03 ± 3.98 | 23.10 ± 3.98 | 16.75 ± 4.25 | 111.84 ± 54.09 | 111.86 ± 101.57 |
p < 0.05 vs aCSF