Figure 1. Longitudinal monitoring of tumor growth using MRI.

(A) T₂-weighted fast spin echo datasets (TE/TR = 16/1403 ms) at 136 µm resolution demonstrating the visual difference in tumor growth pre-treatment and on days 4, 9 and 15 for all groups. (B) Percent relative change in average tumor volumes from day 0 showing significantly larger tumors for the controls and MK1775 treated animals compared to the Gem and Combo groups on day 4. Treatments were administered on days 1, 3, 8 and 10.