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. Author manuscript; available in PMC: 2013 Dec 16.
Published in final edited form as: Am J Gastroenterol. 2012 Jun 12;107(9):1388–1398. doi: 10.1038/ajg.2012.137

Figure 6. Decreased Frequency of Clinical Outcomes to Year 7 in Both Untreated Control and Treated Groups is Associated with Improvement in Hepatic Inflammation at Year 1.5.

Figure 6

The cumulative percentage of patients with clinical outcomes (defined in Materials and Methods) from Kaplan-Meier life table analyses are shown. Patients were categorized according to their randomized untreated control or treated status and the change in hepatic inflammation between baseline and year 1.5 (y-axis) (A) or change in serum ALT between baseline and year 1.5 (y-axis) (B). For panel A, sample sizes in the control group were: HAI worse (n = 109), HAI same (n = 203), HAI improved (n = 102) and in the treated group were: HAI worse (n = 73), HAI same (n = 178), HAI improved (n = 169). For panel B, sample sizes in the control group were: ALT worse (n = 61), ALT same (n = 248), ALT improved (n = 105) and in the treated group were: ALT worse (n = 73), ALT same (n = 200), ALT improved (n = 147). P values for differences among the three groups were derived from a Cox regression analysis for the control and treated groups evaluated separately.