Table 1.
Control | PEG IFN | P-value | |
---|---|---|---|
Patient Number | 414 | 420 | NA |
Nonresponders, % | 63.5 | 62.4 | 0.891 |
Breakthrough/Relapsers, % | 15.9 | 15.7 | |
Express,2 % | 20.5 | 21.9 | |
Age | 49.6 (6.7) | 51.0 (7.3) | 0.005 |
Male, % | 72.7 | 70.5 | 0.48 |
Caucasian, % | 72.2 | 71.7 | 0.86 |
Body Mass Index | 29.8 (5.2) | 29.7 (5.3) | 0.83 |
ALT/ULN | 2.22 (1.79) | 2.10 (1.59) | 0.32 |
Log10 HCV RNA | 6.45 (0.50) | 6.46 (0.50) | 0.93 |
Genotype 1, % | 92.3 | 95.9 | 0.02 |
Ishak Inflammation | 7.5 (2.0) | 7.6 (2.1) | 0.49 |
Ishak Fibrosis | 4.1 (1.3) | 4.0 (1.2) | 0.58 |
Ishak Fibrosis 5–6, % | 39.4 | 38.1 | 0.71 |
All values represent Means (± SD) unless otherwise indicated.
Compares the distribution of all 3 subsets (Nonresponders, Breakthrough/Relapsers and Express patients) between Control and Treated groups.
Express patients received full-dose peginterferon/ribavirin therapy outside of the HALT-C Trial prior to enrollment.7