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Regional Manhattan plot for FAM53B, showing the meta-analysis P-value from EAs and AAs in the discovery and SAGE, as well as a single point for the phase 1–3 meta-analysis result (the highest purple dot on the graph). Since the result is driven primarily by AAs, the LD heat map is based on AAs also. Imputed SNPs are shown as circles, and genotyped SNPs as squares.
