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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Neuropharmacology. 2013 Aug 22;0:10.1016/j.neuropharm.2013.08.001. doi: 10.1016/j.neuropharm.2013.08.001

Table 2. Classification of rats by cocaine-induced locomotor activity.

Acute Cocaine Groups Acute 1 and Acute 2
Group Classification Habituation LMA
(cm/30 min)
Cocaine LMA
(cm/30 min)
Baseline Mean Mean Median
Acute 1 Vehicle (n = 8) 83 ± 36 342 ± 65
Acute 2 Vehicle (n = 6) 109 ± 50 569±140
Acute 1 Cocaine (n = 16) 135 ± 48 880±120
Acute 2 Cocaine (n = 18) 78 ± 41 1088±330
Acute 1 LCR (n = 8) 226±120 347±102 772
HCR (n = 8) 95 ± 59 1413±180
Acute 2 LCR (n = 9) 74 ± 64 429 ± 74 813
HCR (n = 9) 81 ± 55 1747 ± 590

Comparison of cocaine-induced locomotor activity (10 mg/kg, i.p.) in all rats and rats classified as LCRs and HCRs in groups Acute 1 and Acute 2. Data are presented as mean values ± SEM and represent the sum of activity over the first 30 min post-injection.