Figure 3. Effect of exogenous IL-1β on MMP-3 activity in odontoblast-like cells.

Effect of exogenous IL-1β on MMP-3 activity in odontoblast-like cells derived from iPS cells, ES cells and KN-3, as evaluated by the immunoprecipitation-MMP-3 assay. The cells were incubated in serum-free medium in the absence or presence of IL-1βfor the times indicated (6 h  =  white bars, or 12 h  =  black bars). Data are presented as the mean ± SD of six independent experiments; (vs. control, *P<0.05).