Table 4. Flow cytometry results in the non-diabetic and diabetic mice and rabbit animal models before and ten days after wounding.
C57BL/6 Mice Before Wounding(CMB, n=34) | C57BL/6 Mice After Wounding(CMW, n=7) | STZ-Diabetic C57BL/6 Mice Before Wounding(DMB, n=11) | STZ-Diabetic C57BL/6 Mice After Wounding(DMW, n=21) | |
---|---|---|---|---|
CD34+FLK-1+ a | 20 (0:81) | 40 (10:220) | 25 (10:150) | 270 (130:600) |
CD34+CD133+ b | 0 (0:10) | 30 (10:40) | 10 (0:89) | 40 (27:69) |
FLK-1+CD133+ | 80 (20:206) | 140 (50:270) | 128 (10:310) | 210 (100:384) |
CD34+FLK-1+CD133+ c | 0 (0:13) | 30 (10:40) | 9 (0:50) | 70 (64:150) |
Rabbits Before Wounding(CRB, n=8) | Rabbits After Wounding(CRW, n=7) | Alloxan-Diabetic Rabbits Before Wounding(DRB, n=8) | Alloxan-Diabetic Rabbits After Wounding(DRW, n=13) | |
CD34+ | 132 (102:225) | 146 (30:558) | 665 (86:1956) | 427 (249:3469) |
CD34+KDR+ d | 105 (55-163) | 87 (39:272) | 669 (110:1246) | 273 (124:1134) |
CD34+CD133+ e | 0 (0:4) | 4 (0:25) | 63 (12:249) | 39 (4:659) |
KDR+CD133+ f | 172 (108:251) | 127 (58:152) | 439 (359:887) | 580 (59:1105) |
CD34+KDR+CD133+ g | 28 (2:35) | 6 (0:24) | 103 (12:238) | 51 (10:167) |
As the data was nonparametrically distributed the Kruskal - Wallis test was employed.
Flow cytometry results are presented as events/106
a: CMB vs DMB: p <0.05, DMB vs DMW: p<0.01; b: CMB vs CMW: p<0.05; c: CMB vs CMW: p <0.05, DMB vs DMW: p<0.01, CMW vs DMW: p<0.01; d: CRW vs DRW: p<0.05; e: CRB vs DRB: p<0.05, CRW vs DRW: p<0.05; f: CRB vs DRB: p<0.05, CRB vs CRW: p<0.05; g: CRB vs DRB: p<0.05, CRW vs DRW: p<0.05.