Table 1. Compound 1 IC₅₀ values for each inflammatory mediator.

	IC50 ± S.D. (μM)
Mediator	LPS	Pam3Cys	Poly I:C
NO	7.54 ± 2.82	n.a.	n.a.
TNF	9.16 ± 0.83	5.28 ± 0.87	1.46 ± 0.11
IL-6	12.25 ± 0.40	8.04 ± 0.25	3.26 ± 0.94
IL-1β	2.75 ± 0.68	n.a.	n.a.
IP-10	3.73 ± 0.57	n.a.	7.10 ± 0.97

Values represent average of IC₅₀ from three independent experiments ± S.D.

IC₅₀ (positive control) = 1.47 ± 0.83 μM (value corresponds to the inhibition of NO production by the iNOS inhibitor L-N6).

n.a., not analyzed.