Table 1. Baseline Characteristics:.
All | No PH | PH | ||
---|---|---|---|---|
(n=3282) Mean ± SD | (n=3059) Mean ± SD | (n=223) Mean ± SD | p-value* | |
Age | 56.1 ± 12.6 | 55.4 ± 12.6 | 65.4 ± 9.4 | <0.0001 |
Male | 32.5% | 33.2% | 22.9% | 0.002 |
BMI Category | ||||
Normal | 15.2% | 15.6% | 10.3% | |
Overweight | 33.7% | 34.1% | 28.2% | |
Obese | 51.0% | 50.3% | 61.4% | 0.004 |
Systolic BP (mm Hg) | 126.5 ± 18.2 | 125.9 ± 17.9 | 133.9 ± 21.4 | <0.0001 |
Diastolic BP (mm Hg) | 78.2 ± 10.4 | 78.4 ± 10.4 | 75.6 ± 10.7 | 0.0001 |
Pulse Pressure (mm Hg) | 48.3 ± 15.8 | 47.5 ± 15.3 | 58.3 ± 18.9 | <0.0001 |
Hypertension | 60.9% | 59.4% | 82.1% | <0.0001 |
Diabetes | 24.6% | 23.2% | 42.6% | <0.0001 |
Coronary Heart Disease | 8.3% | 7.9% | 13.9% | 0.002 |
Severe Mitral/ Aortic Valvular disease | 0.2% | 0.1% | 1.8% | <0.0001 |
Chronic Lung Disease | 7.0% | 6.5% | 13.9% | <0.0001 |
Smoking History | ||||
Never Smoked | 68.1% | 68.3% | 64.9% | |
Former Smoker | 19.8% | 19.6% | 23.4% | |
Current Smoker | 12.1% | 12.1% | 11.7% | 0.376 |
FEV1 % predicted | 91.7 ± 18.2 | 92.4 ± 17.7 | 82.2 ± 21.8 | <0.0001 |
FVC % predicted | 91.0 ± 18.6 | 91.5 ± 18.1 | 84.7 ± 23.8 | <0.0001 |
FEV1/FVC | 80.2 ± 9.3 | 80.5 ± 9.1 | 76.4 ± 10.9 | <0.0001 |
Spirometry Profile: | ||||
Normal | 69.6% | 70.9% | 50.2% | |
Obstruction | 9.5% | 8.9% | 18.2% | |
Restriction | 21.0% | 20.2% | 31.5% | <0.001 |
* Comparison between PH and no PH groups.