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. 2013 Dec 16;8(12):e84264. doi: 10.1371/journal.pone.0084264

Table 1. Baseline Characteristics:.

All No PH PH
(n=3282) Mean ± SD (n=3059) Mean ± SD (n=223) Mean ± SD p-value*
Age 56.1 ± 12.6 55.4 ± 12.6 65.4 ± 9.4 <0.0001
Male 32.5% 33.2% 22.9% 0.002
BMI Category
Normal 15.2% 15.6% 10.3%
Overweight 33.7% 34.1% 28.2%
Obese 51.0% 50.3% 61.4% 0.004
Systolic BP (mm Hg) 126.5 ± 18.2 125.9 ± 17.9 133.9 ± 21.4 <0.0001
Diastolic BP (mm Hg) 78.2 ± 10.4 78.4 ± 10.4 75.6 ± 10.7 0.0001
Pulse Pressure (mm Hg) 48.3 ± 15.8 47.5 ± 15.3 58.3 ± 18.9 <0.0001
Hypertension 60.9% 59.4% 82.1% <0.0001
Diabetes 24.6% 23.2% 42.6% <0.0001
Coronary Heart Disease 8.3% 7.9% 13.9% 0.002
Severe Mitral/ Aortic Valvular disease 0.2% 0.1% 1.8% <0.0001
Chronic Lung Disease 7.0% 6.5% 13.9% <0.0001
Smoking History
Never Smoked 68.1% 68.3% 64.9%
Former Smoker 19.8% 19.6% 23.4%
Current Smoker 12.1% 12.1% 11.7% 0.376
FEV1 % predicted 91.7 ± 18.2 92.4 ± 17.7 82.2 ± 21.8 <0.0001
FVC % predicted 91.0 ± 18.6 91.5 ± 18.1 84.7 ± 23.8 <0.0001
FEV1/FVC 80.2 ± 9.3 80.5 ± 9.1 76.4 ± 10.9 <0.0001
Spirometry Profile:
Normal 69.6% 70.9% 50.2%
Obstruction 9.5% 8.9% 18.2%
Restriction 21.0% 20.2% 31.5% <0.001

* Comparison between PH and no PH groups.