Figure 4.
Concentrations and activation of iNKT cells (invariant natural killer T cells) in the blood and gut mucosal compartments in persons with and without HIV-1 infection. (a) The concentrations of total iNKT cells in the blood and gut mucosal compartments are plotted, as well as (b) the ratios of the CD4+ to CD4− iNKT cells in each of these compartments. Concentrations and expression of CCR5 and human leukocyte antigen (HLA)-DR are plotted for the (c–e) CD4+ and (f–h) CD4 − iNKT-cell subsets. Persons with (gray boxes) and without (white boxes) HIV-1 infection are compared.