Table 4. Multivariate analysis of overall survival in patients with stage 4 gastric cancer after adjustment on the propensity score.
Variate | HRa | 95% Cl | P |
Treatment | 0.000 | ||
Non-curative surgery+chemotherapy | 0.36 | 0.25–0.51 | |
Chemotherapy only | 1 | reference | |
Ascites | 0.022 | ||
No | 0.57 | 0.35–0.92 | |
Yes | 1 | reference | |
Serum CEA | 0.033 | ||
< the median | 0.68 | 0.48–0.97 | |
≥ the median | 1 | reference | |
Serum CA19-9 | 0.032 | ||
< the median | 0.68 | 0.48–0.97 | |
≥ the median | 1 | reference | |
Second-line chemotherapy | |||
No | 1.46 | 1.02–2.10 | 0.037 |
Yes | 1 | reference | |
Propensity score | 1.21 | 0.81–1.80 | 0.349 |
Abbreviations: Stage 4, including metastatic and recurrent gastric cancer; HRa, hazard ratio adjusted on the propensity score in 4 strata; CI, confidence interval; CEA, baseline carcinoembryonic antigen; CA19-9, baseline carbohydrate antigen 19-9.