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. 2013 Dec 16;8(12):e84649. doi: 10.1371/journal.pone.0084649

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Platelets were isolated from ROCK1-deficient mice and littermate wild-type controls and stimulated with the indicated concentrations of collagen. Aggregation and ATP secretion were measured in a lumi-aggregometer. The traces shown are representative of at least 3 independent experiments.