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. 2013 Dec 16;8(12):e84649. doi: 10.1371/journal.pone.0084649

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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(A) Tail-bleeding time. (B and C) Endothelial injury was induced by light/dye in the cremasteric venules and thrombus onset (B) and occlusion time (flow cessation; C) were monitored by intravital microscopy in ROCK1^-/- (n= 7) and wild-type mice (n= 8). The P value in (C) was determined by one-way ANOVA.