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. 2013 Nov 11;89(9):401–417. doi: 10.2183/pjab.89.401

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© 2013 The Japan Academy

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Schematic of the QCM biosensor operation for monitoring a binding reaction between biomolecules A and B. k_a and k_d are association and dissociation velocity constants, respectively, and C_A denotes the concentration of injected analyte. f and Δf are fundamental resonance frequency and frequency change, respectively. Δm and m_q are adsorbed mass and mass of the quartz resonator, respectively.