Table 1. Genotype counts and allele frequencies for the S422L variant in European, Middle Eastern, Jewish non-Ashkenazi and Ashkenazi Jewish populations.
KCNJ8 genotype | |||||
---|---|---|---|---|---|
Country | N | CC | CT | TT | T allele frequency (%) |
Europe | |||||
France | 66 | 66 | 0 | 0 | 0.00 |
Germany | 10 | 10 | 0 | 0 | 0.00 |
Netherland | 68 | 68 | 0 | 0 | 0.00 |
Poland | 27 | 27 | 0 | 0 | 0.00 |
Romania | 27 | 27 | 0 | 0 | 0.00 |
Russia | 24 | 22 | 0 | 0 | 0.00 |
Ukraine | 40 | 40 | 0 | 0 | 0.00 |
Total | 262 | 262 | 0 | 0 | 0.00 |
Middle East | |||||
Iran | 42 | 42 | 0 | 0 | 0.00 |
Turkey | 8 | 8 | 0 | 0 | 0.00 |
Total | 50 | 50 | 0 | 0 | 0.00 |
Jewish non-Ashkenazi | |||||
Iran | 20 | 20 | 0 | 0 | 0.00 |
Iraq | 26 | 26 | 0 | 0 | 0.00 |
Turkey | 25 | 25 | 0 | 0 | 0.00 |
Italy (Rome) | 48 | 45 | 3 | 0 | 3.13 |
Total | 119 | 116 | 3 | 0 | 1.26 |
Ashkenazi Jewish | |||||
France | 35 | 29 | 6 | 0 | 8.57 |
Germany | 9 | 8 | 1 | 0 | 5.56 |
Hungary | 8 | 8 | 0 | 0 | 0.00 |
Netherlands | 16 | 15 | 1 | 0 | 3.13 |
Poland | 70 | 67 | 3 | 0 | 2.14 |
Romania | 19 | 19 | 0 | 0 | 0.00 |
Russia | 8 | 8 | 0 | 0 | 0.00 |
Ukraine | 25 | 22 | 3 | 0 | 6.00 |
USA | 101 | 92 | 9 | 0 | 4.46 |
Total | 291 | 268 | 23 | 0 | 3.95 |