Pedigree of Family A. Roman numerals indicate generation and Arabic numbers individuals in each generation. Filled symbols indicate affected individual; light gray indicates tested for duplication and not present, medium gray indicates not tested and black indicates tested and individual has duplication. Numbers inside symbols indicate number of individuals. DUP, duplication; NT, not tested; NRL, normal; ABN EEG, abnormal EEG; ADHD, attention deficit hyperactivity disorder; DEV DELAY, developmental delay; ODD, oppositional defiant disorder.