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. 2013 Dec 17;7:242. doi: 10.3389/fnins.2013.00242

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Copyright © 2013 Kelly and Goodson.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Representative knockdown of VT production as shown in a colchicine-treated pilot subject that received infusions of scrambled oligonucleotides in the left hemisphere and VT antisense oligonucleotides in the right hemisphere. Inset: Magnified view of VT-ir neurons in the BSTm. Scale bar = 100 μm; 50 μm for inset. Abbreviations: AC, anterior commissure; LS, lateral septum; MS, medial septum; nPC, nucleus of the pallial commissure; v, ventrical. (B) Data from a within-subjects validation experiment, showing the percent of total BSTm VT-ir neurons that were observed in hemispheres infused with scrambled (control) and antisense oligonucleotides. ^*p = 0.01.