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. 2013 Dec 16;210(13):2981–2990. doi: 10.1084/jem.20130417

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© 2013 Firth et al.

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Figure 4. — Proinflammatory cytokines IL-12 and type I IFNs drive proliferation of Ly49H⁺ NK cells in Nfil3^−/− mice during MCMV infection. Nfil3^−/− mice were pretreated with the indicated blocking antibodies (or PBS as a control) 24 h before MCMV infection, and the percentage of Ly49H⁺ NK cells in spleen (A) and liver (B) was determined by flow cytometry at day 7 PI. (C and D) Absolute numbers of Ly49H⁺ NK cells at day 7 PI were determined in spleen (C) and liver (D). Error bars for all graphs show SEM and data are representative of n = 3 mice per group, and the experiments were performed twice.