Table 2.

TILs are associated with specific mutations in GBM

Gene	n	Chi square p-value (0, 1+, 2+)	Chi square p-value (0 vs 1+, 2+ combined)	Chi square p-value (0, 1+ combined vs 2+)
TP53	33	0.13	0.06	0.15
PTEN	29	0.15	0.06	0.44
EGFR	26	0.82	0.54	1.00
NF1	16	0.03	0.74	0.04
RB1	10	0.04	0.04	0.22
PIK3R1	9	0.67	0.49	1.00
PIK3CA	7	0.72	1.00	0.50
IDH1	4	0.53	1.00	0.32
ERBB2	0	-	-	-

Chi-square test was used to examine associations between lymphocytes (0, 1+, 2+) and mutations (0, 1)

Fisher’s exact test was used when 25% of the cells had <5 observations

Effective Sample Size 99

Categories were combined to identify associations driven by cases with either complete absence or abundance of lymphocytes