Figure 2.
Immunohistochemistry of surviving Patch/Patch (Ph/Ph) on Balb/c background. (A, C, E) Embryonic day (E)13 wildtype and (B, D, F) Ph/Ph mutant transverse sections stained for β3-Tubulin (A–D) and Tyrosine hydroxylase (E, F) expression. Note similar β3-Tubulin in both wild-type and mutant neural tube and dorsal root ganglia (A, B), and within sympathetic ganglia (arrows in [C and D]). Similarly, Tyrosine hydroxylase expression is equivalent in wildtype (E, arrow) and Ph/Ph (F, arrow) sympathetic ganglia. Nt, neural tube; Drg, dorsal root ganglia. Scale bars: e, f = 200 μm.
