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Survival of Patch Homozygous Mutants on a Balb/c-enriched Background
| Oldest surviving Ph/Ph |
Typical phenotype | |
|---|---|---|
| Original C57 | E10.5 (n = 21) | Enlarged heart, wavy/kinked neural tube |
| Third generation | E13.5 (n = 5) | Cleft face, PTA, blebs |
| Sixth generation | E17.5 (n = 17) | Cleft face, PTA, omphalocele, blebs |
Patch/Patch, Ph/Ph; E, embryonic day; PTA, persistent truncus arteriosus.
