Table 2.

Bone markers in CKD

Gene symbol	Gene name	Gene ID	References
ACP5	Acid phosphatase 5, tartrate resistant	54	[17]
ALPL	Alkaline phosphatase, liver/bone/kidney	249	[19]
B2M	β-2-microglobulin	567	[17]
BGLAP	Bone γ-carboxyglutamate (gla) protein (osteocalcin)	632	[17]
BMP1	Bone morphogenetic protein 1	649	[20]
BMP10	Bone morphogenetic protein 10	27302	[20]
BMP15	Bone morphogenetic protein 15	9210	[20]
BMP2	Bone morphogenetic protein 2	650	[20]
BMP3	Bone morphogenetic protein 3 (osteogenic)	651	[20]
BMP4	Bone morphogenetic protein 4	652	[20]
BMP5	Bone morphogenetic protein 5	653	[20]
BMP6	Bone morphogenetic protein 6	654	[20]
BMP7	Bone morphogenetic protein 7 (osteogenic protein 1)	655	[17]
BMP8A	Bone morphogenetic protein 8a	353500	[20]
BMP8B	Bone morphogenetic protein 8b (osteogenic protein 2)	656	[20]
BMPR1A	Bone morphogenetic protein receptor, type IA	657	[20]
BMPR1B	Bone morphogenetic protein receptor, type IB	658	[20]
BMPR2	Bone morphogenetic protein receptor, type II (serine/threonine kinase)	659	[20]
COL1A1	Collagen, type I, α-1	1277	[17]
COL1A2	Collagen, type I, α-2	1278	[17]
CSF1	Colony stimulating factor 1 (macrophage)	1435	[20]
CSF2	Colony stimulating factor 2 (granulocyte-macrophage)	1437	[20]
CTSL	Cathepsin L	1514	[17]
FGF23	Fibroblast growth factor 23	8074	[16]
FN1	Fibronectin-1	2335	[20]
GDF5	Growth differentiation factor 5	8200	[31]
GDF6	Growth differentiation factor 6	392255	[31]
GDF7	Growth differentiation factor 7	151449	[31]
IFNG	Interferon, γ	3458	[20]
IGF-1	Insulin-like growth factor 1 (somatomedin C)	3479	[17]
IL11	Interleukin-11	3589	[20]
IL1A	Interleukin-1, α	3552	[20]
IL1B	Interleukin-1, β	3553	[20]
IL6	Interleukin-6 (interferon, β-2)	3569	[20]
LEP	Leptin (obesity homologue, mouse)	3952	[28]
MEPE	Matrix, extracellular phosphoglycoprotein with ASARM motif (bone)	56955	[17]
PHEX	Phosphate regulating endopeptidase homologue, X-linked (hypophosphatemia, vitamin D resistant rickets)	5251	[17]
PLAU	Plasminogen activator, urokinase	5328	[20]
PTGES2	Prostaglandin E synthase 2	80142	[20]
PTH	Parathyroid hormone	5741	[16]
SERPINE1	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	5054	[20]
SPARC	Secreted protein, acidic, cysteine-rich (osteonectin)	6678	[20]
SPP1	Secreted phosphoprotein 1 (osteopontin, bone	6696	[20]
	sialoprotein I, early T-lymphocyte activation 1)
TGFB1	Transforming growth factor-β1 (Camurati-Engelmann disease)	7040	[20]
TNF	Tumour necrosis factor (TNF superfamily, member 2)	7124	[20]
TNFRSF11B	Tumour necrosis factor receptor superfamily, member 11b (osteoprotegerin)	4982	[17]