Table 8.
Gene ontology analysis of the genes affected in WTPCIR versus KOPCIR comparison
| Relevant functions | P-value | No of Molecules |
|---|---|---|
| Cellular compromise | 9.02E-3 – 4.43E-2 7 | 7 |
| Lipid metabolism | 9.02E-3 – 4.43E-2 6 | 6 |
| Organismal injury and abnormalities | 9.02E-3 – 4.43E-2 6 | 6 |
| Cardiovascular disease | 9.02E-3 – 4.43E-2 4 | 4 |
| Organismal development | 9.02E-3 – 4.43E-2 4 | 4 |
| Carbohydrate metabolism | 9.02E-3 – 4.43E-2 3 | 3 |
| Endocrine system disorders | 9.02E-3 – 4.43E-2 3 | 3 |
| Small molecule biochemistry | 9.02E-3 – 4.43E-2 23 | 23 |
| Respiratory system development and function | 9.02E-3 – 4.43E-2 2 | 2 |
| Molecular transport | 9.02E-3 – 4.43E-2 12 | 12 |
| Skeletal and muscular system development and function | 9.02E-3 – 4.43E-2 11 | 11 |
| Skeletal and muscular disorders | 9.02E-3 – 4.38E-2 9 | 9 |
| Tissue development | 9.02E-3 – 4.38E-2 12 | 12 |
| Organ Development | 9.02E-3 – 3.56E-2 6 | 6 |
| DNA replication, recombination, and repair | 9.02E-3 – 3.56E-2 5 | 5 |
| Cardiovascular system development and function | 9.02E-3 – 2.68E-2 4 | 4 |
| Cell Signalling | 8.21E-3 – 4.43E-2 5 | 5 |
| Cellular assembly and organization | 7.08E-6 – 4.43E-2 17 | 17 |
| Embryonic development | 6.85E-3 – 4.43E-2 9 | 9 |
| Cell death | 6.85E-3 – 4.43E-2 8 | 8 |
| Cellular growth and proliferation | 4.49E-4 – 4.43E-2 15 | 15 |
| Cell-to-cell signalling and interaction | 4.49E-4 – 4.43E-2 13 | 13 |
| Organismal survival | 3.02E-2 – 4.11E-2 15 | 15 |
| Vitamin and mineral metabolism | 2.68E-2 – 4.43E-2 2 | 2 |
| Amino acid metabolism | 2.44E-2 – 4.43E-2 9 | 9 |
| Post-translational modification | 2.44E-2 – 4.43E-2 8 | 8 |
| Protein trafficking | 2.03E-2 – 2.03E-2 5 | 5 |
| Cellular function and maintenance | 1.80E-2 – 4.43E-2 6 | 6 |
| Tissue morphology | 1.65E-3 – 4.43E-2 16 | 16 |
| Gene expression | 1.18E-3 – 4.43E-2 10 | 10 |