Table 1.

Biodistribution of ^99mTc-DTPA in normal healthy F-344 rats

	30 min	60 min	180 min
Blood	1.08 ± 0.21	0.37 ± 0.04	0.19 ± 0.01
Heart	0.27 ± 0.04	0.10 ± 0.01	0.06 ± 0.01
Lung	0.56 ± 0.08	0.24 ± 0.02	0.14 ± 0.01
Thyroid	0.54 ± 0.18	0.21 ± 0.02	0.19 ± 0.03
Pancreas	0.20 ± 0.00	0.08 ± 0.01	0.05 ± 0.01
Liver	0.80 ± 0.20	0.76 ± 0.04	0.52 ± 0.09
Spleen	0.75 ± 0.11	0.97 ± 0.13	0.76 ± 0.16
Kidney	8.38 ± 1.17	11.33 ± 0.49	10.20 ± 1.17
Stomach	0.39 ± 0.06	0.20 ± 0.05	0.14 ± 0.02
Intestine	0.38 ± 0.00	0.24 ± 0.07	0.12 ± 0.02
Brain	0.03 ± 0.01	0.01 ± 0.00	0.01 ± 0.00
Muscle	0.12 ± 0.01	0.04 ± 0.01	0.02 ± 0.00
Bone	0.27 ± 0.04	0.15 ± 0.02	0.08 ± 0.01
P/blood	0.19 ± 0.04	0.20 ± 0.01	0.25 ± 0.02
P/muscle	1.72 ± 0.10	1.74 ± 0.23	1.92 ± 0.19

Values are % of injected dose per gram of tissue weight and represent the mean ± standard errors of the mean of data from 3 animals per time interval

P pancreas