Figure 4.
Positions of the HER2 exon 20 insertions identified in the present study and comparison with the spectrum of EGFR exon 20 insertion mutations identified at our institution over a 3 year period. Insertions in HER2 show significantly less heterogeneity compared to EGFR with over 80% of HER2 alterations being represented by the A775_G776insYVMA.