Table 1.
Patient Characteristics
| Characteristic | CrCl ≤ 60 mL/min |
CrCl > 60 mL/min |
|---|---|---|
| Number of Patients | 14 | 18 |
| Median Age, Years (Minimum-Maximum) | 71.(57–80) | 54 (40–70) |
| KPS≥ 80 | 12/14 (86%) | 17/18 (94%) |
| MSKCC 0-1 | 10/14 (71%) | 14/18 (77%) |
| Clear Cell Variant | 6/14 (43%) | 14/18 (77%) |
| Nephrectomy | 14/14 (100%) | 15/18 (83%) |
| Median CrCl in mL/min (Minimum-Maximum) | 47.5 (32–59) | 95.5 (64–164) |
| Median Cr in mg/dL (Minimum-Maximum) | 1.6 (1.1–3.2) | 1.1 (0.9–1.5) |
| Median SBP in mm Hg (Minimum-Maximum) | 143 (104–180) | 145 (94–163) |
| Median DBP in mm Hg (Minimum-Maximum) | 71 (60–100) | 75.5 (38–99) |
| Number of Patients Still Medications at Last Visita | 0/14 | 3/18 |
| Number of Patients Progression Free at Last Visita | 4/14 | 6/18 |
a
Last visit to physician or 06/30/07.
Abbreviations: CrCl = creatinine clearance; DBP = diastolic blood pressure; KPS = Karnofsky performance score; MSKCC = Memorial Sloan-Kettering Cancer Center; SBP = systolic blood pressure